Drug testing

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  • 170302 Confirmation kit

     

    The APAC Confirmation kits are used for specimen collection, packaging and transportation of samples to the toxicology laboratory. With tamperproof bags and security seals, chain of custody is not negotiated!

    Confirmation kits are offered in two different configurations:

    Scope of supply – urine confirmation kit

    • Two specimen jars with screw lids
    • Tamperproof specimen bag with adsorbent pad
    • Four security seals; two to seal the specimen jars, one to seal the transport box and one to attach to the Chain of custody doPurpose of usagcument. Each set of four seals uses a unique number for ease of tracking.
    • Cardboard box to house specimen jar

     

    Scope of supply – oral fluid confirmation kit

    • Two specimen tubes and collection pads. The pads are used to collect oral uid and will change color once su cient uid has been collected. The pad is inserted into the tube containing a saline solution, where after the tube is
    • Tamperproof specimen bag with adsorbent pad
    • Four security seals; two to seal the specimen tubes, one to seal the transport box and one to attach to the Chain of custody doc closed with a rubber corkument. Each set of four seals uses a unique number for ease of tracking.
    • Cardboard box to house specimen tubes

     

     

    Request for a free sample here

    Download APAC Confirmation kit Data sheet here

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  • APACCUp 280x350

     

    A one-step test for the detection of drugs of abuse in urine.

    Why choose the APAC Cup?

    • Design by an Australian science team with over 15 years experience of Immunoassay devices.
    • Quality approval with AS4308:2008 certification and listed with TGA.
    • Tailor made to suit our clients requirements. Choose from over 20 drugs.
    • Proven track record – It is used by major Correctional departments as well as private clients for work place testing since many years.

     

    Request for a free sample here

     

    Download APAC Multipanel cup Data sheet here

    The APAC Cup is designed by an Australian science team

    In 2010, APAC Security was awarded a government contract to supply Drug of Abuse screening cups to corrections. Quite soon we realised that the configurations of the drugs were not suitable for corrections and we were not able to find any alternatives, in Australia nor Internationally. Since we had over 10 years experience from the development of the BIOSENS system, which is based on an immunoassay based technology, we decided to design our own lateral flow immunoassay cup.

    An immunoassay device, like the APAC Cup, is based on the principle of developing Monoclonal Antibodies, that can detect target molecules like Methamphetamine. Inside the APAC Cup, each detectable drug is represented by a single strip that soaks up urine in a lateral flow. Once the urine “climbs” the strip, it passes through an area where the monoclonal antibodies are attached to the strip. The antibodies mix with the urine and continue to flow upwards, towards a Test line, T-line, which is coated with something similar to Methamphetamine, so called antigen. Importantly, the antigen has a weaker affinity to the antibody, meaning the antibody prefers being attached to the “real” Methamphetamine rather than weaker antigen. If the urine contains none or low concentrations of Methamphetamine, the antibodies will bond to the antigens on the T-line. The less concentration the more antibodies that bond to the T-line. Since the antibodies have been linked with a reddish ink made from gold, you don’t actually see the antibodies but the gold colloid particles. Consequently if the urine contains Methamphetamine, the antibodies will simply pass by, the T-line, as the bonding to the real drug is stronger, meaning no line represents a positive.

    Further reading by Wikipedia

     

    The APAC Cup is quality approved

    Collection and testing of drugs in urine and oral fluid (saliva) are governed by NATA, which is an Australian Authority. The urine standard is named as AS/NZS 4308:2008 and the oral fluid AS 4760:2006. The standards covers issues such as proper collection, chain of custody, initial screening, confirmation analysis and reporting of samples. The requirements for the APAC cup can be found in AS/NZS 4308:2008, Appendix B – “Verification of performance of on-site devices around Cut off”.

    The current standard only involves the six “standard” drugs and defines what concentrations should be considered as negative or non-negative (syntax is non-negative, as the sample can only be confirmed as positive after  a final GCMS or LCMS confirmatory test). As one may realise it is quite important that the community agree to what should be regarded as negative/non-negative, in terms of concentrations, which are defined as follows:

     Type of drug  Cut off ng/ml
     Amphetamine  300
     Methamphetamine  300
     Benzodiacepine  200
     Cocaine  300
     Morphine (Heroine)  300
     THC (Cannabinoids)  50

    Because the cups are not digital e.g.  providing an Opiate negative for 299 and non-negative for 301, the standard stipulates that the cup must show a negative for the cut off minus 30% and a non-negative for the cut-off plus 25%. As an example the APAC cup must display a Heroine negative for a urine concentration of 210 ng/ml (nano gram per micro litre) and below & a non-negative for a concentration of 375 ng/ml and above. Consequently, APAC Security sent a number of cups to a government laboratory who tested the cups against the cut offs. A Certificate of compliance was issued after the final test in 2016.

     

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